events, seminars
November 3rd, 2023 – Jean-François Brunet (IBENS – ENS)- Genetic architecture of the autonomic nervous system
A general structure for the autonomic nervous system, divided into sympathetic and parasympathetic arms, was codified by John Newport Langley at the beginning of the XXth century. We propose a revision of this scheme based on neuron types. The “sacral… Continue reading
events, seminars
October 6th, 2023 – Sarah Genon (Research Center Jülich, Germany) – From the complexity of brain organization to challenges in brain-behaviour mapping
Understanding brain-behaviour relationships in humans remains as one of the most complex scientific question. For a few decades, data offered by neuroimaging approaches, in particular MRI, have been under intense scientific investigations and methodological questioning. These have highlighted continuous challenges… Continue reading
events, seminars
September 29th 2023 – Eric Burguière (ICM, Paris) – Translational approach to investigate the neurofunctional bases of repetitive behaviours
Repetitive behaviors are acquired through practice and, under normal conditions, allow motor or cognitive processes to be efficiently automated in everyday life. However, a loss of control in the regulation of these processes can lead to their pathological overexpression. These… Continue reading
events, seminars
September 22nd, 2023 – Valérie Doyère (Paris-Saclay Institute of Neuroscience / NeuroPsi)- The amygdala and the temporal expectancy of a reinforcer
When a sound predicts the potential arrival of a reinforcer, the subject learns the time at which that reinforcer may arrive or is available. The amygdala, and in particular its basolateral (BLA) part is critical for the emotional/motivational aspect of… Continue reading
events, seminars
July 7th, 2023 – Mariano Soiza-Reilly (Institute of Physiology, Molecular Biology and Neurosciences – University of Buenos Aires – CONICET)- Synaptic refinement of afferents to raphe 5-HT neurons: Implications for psychiatric disorders
Psychiatric disorders including depression, anxiety and stress vulnerability represent main disabling conditions for individual’s life. Recent studies suggest that many aspects of these pathologies could have an early origin during childhood. Our goal is to investigate how maladaptive neurodevelopmental mechanisms… Continue reading
events, seminars
May 15, 2023 – Kishore Kuchibhotla (Johns Hopkins University, Baltimore, USA)- Insights and strategies during sensorimotor learning
Large-scale neural recordings provide an opportunity to better understand how the brain implements critical behavioral computations related to goal-directed learning. In this seminar, I will argue that re-visiting our understanding of the shape of the learning curve and… Continue reading
events, seminars
May 12, 2023 – Jean-François Perrier (University of Copenhagen, Denmark) – Understanding the cellular mechanisms responsible for neurodevelopmental encephalopathies – the example of STXBP1 encephalopathies
De novo mutations in Stxbp1 are among the most prevalent causes of neurodevelopmental disorders, and lead to haploinsufficiency, cortical hyperexcitability, epilepsy and other symptoms. Given that Munc18-1, the protein encoded by … Continue reading
grants, opportunities
Open Mind Master students grants – 2023
Pilar Acebo, whose project Role of alpha-secretase ADAM10 in the myelination and remyelination of the Central Nervous System is supervised by Delphine Meffre (Team Myelination and pathologies of the nervous system, T3S Laboratory, UMR-S 1124 INSERM).
Alexia Gérard,… Continue reading
events, seminars
March 3, 2023 – Francesco BATTAGLIA (Radbound University, The Netherlands) – Hippocampal gamma oscillations mediating cortico-hippocampal oscillations and shaping hippocampal temporal code.
Theta sequences and phase precession shape hippocampal activity and are considered key underpinnings of memory formation. Theta sequences are sweeps of spikes from multiple cells, tracing trajectories from past to future. Phase precession is the correlation between theta firing phase… Continue reading
events, seminars
February 10, 2023 – Mohamed JABER (Université de Poitiers, France) – Genetic and environmental animal models of autism reproduce the spectrum of the disease
Genetic and environmental factors increase autism spectrum disorder (ASD) incidence and this has led to the generation of corresponding animal models, with some showing strong construct and face validity.
In this line, we have recently published a series of several studies on ASD environmental… Continue reading