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  • events, seminars

    Novembre 25, 2022 – Hélène Puccio (Institut NeuroMyoGene, Université Claude Bernard, Lyon and Institut de Génétique et de Biologie Moléculaire et Cellulaire, Université de Strasbourg) – Disruption of the CoQ10 biosynthetic Complex Q causes mitochondrial dysfunction and Ca2+ imbalance in Purkinje neurons in COQ8A-ataxia

    COQ8A-Ataxia is a rare form of neurodegenerative disorder due to mutations in the COQ8A gene. The encoded mitochondrial protein is involved in the regulation of Coenzyme Q10 biosynthesis. Previous studies on the constitutive Coq8a-/- mice indicated specific alterations of cerebellar…  Continue reading

    events, seminars

    December 2, 2022 – Gabriel Lepousez (Perception and Memory Laboratory, Pasteur Institute) – How brain circuits sense and integrate peripheral immune signals

    Upon infection, bacterial compounds, and the pro-inflammatory cytokines they elicit, induce a complex response coordinated by the brain and known as “sickness behavior”. This response induces stereotyped behavioral changes (reduced locomotion and food intake, social avoidance), metabolic adjustments (fever, glycemia),…  Continue reading

    events, seminars

    9 Décembre 2022 – Jean-Michel Perrin (Institute of Biology Paris-Seine) – Reconstructing rodent and human neuronal networks to model neurodegenerative syndromes

    Human brain is a complex organ composed of several hundred billions of cells and even more numerous interconnected cellular interactions. There is a high demand for experimental models to study these interactions in various contexts, ranging from cognitive sciences…  Continue reading

    events, seminars

    October 7, 2022 – Fekrije Selimi  (Collège de France, Paris)- The developmental history of the molecular synaptic code controlling excitatory connectivity

    The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with a limited number of partners and on precise subcellular localizations. Understanding what controls this specificity is…  Continue reading

    events, seminars

    September 30, 2022 – Valeria Cavalli (Washington University School of Medicine, USA) – Satellite Glial Cells in sensory nervous system health, injury and disease

    Exceptionally this seminar will take place in Salle des thèses (3rd floor) – Saint-Germain-des-Prés Campus, 45 rue des Saints Pères, 75006 Paris Research in my laboratory focuses on elucidating the principles and mechanisms by which peripheral nervous system neurons regenerate,…  Continue reading

    events, seminars

    September 23, 2022 – Sébastien Bouret (ICM, Paris) – Neural basis of decision-making in primates. In the lab and beyond

    The presentation will cover the cognitive and neurobiological functions underlying cost-benefits decision making in primates. After covering data from laboratory experiments, I will present recent studies aimed at understanding how these data can help understand how specific neuro-cognitive operations allow…  Continue reading
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