A general structure for the autonomic nervous system, divided into sympathetic and parasympathetic arms, was codified by John Newport Langley at the beginning of the XXth century. We propose a revision of this scheme based on neuron types. The “sacral…  Continue reading →

Understanding brain-behaviour relationships in humans remains as one of the most complex scientific question. For a few decades, data offered by neuroimaging approaches, in particular MRI, have been under intense scientific investigations and methodological questioning. These have highlighted continuous challenges…  Continue reading →

Repetitive behaviors are acquired through practice and, under normal conditions, allow motor or cognitive processes to be efficiently automated in everyday life. However, a loss of control in the regulation of these processes can lead to their pathological overexpression. These…  Continue reading →

When a sound predicts the potential arrival of a reinforcer, the subject learns the time at which that reinforcer may arrive or is available. The amygdala, and in particular its basolateral (BLA) part is critical for the emotional/motivational aspect of…  Continue reading →

Psychiatric disorders including depression, anxiety and stress vulnerability represent main disabling conditions for individual’s life. Recent studies suggest that many aspects of these pathologies could have an early origin during childhood. Our goal is to investigate how maladaptive neurodevelopmental mechanisms…  Continue reading →

Large-scale neural recordings provide an opportunity to better understand how the brain implements critical behavioral computations related to goal-directed learning. In this seminar, I will argue that re-visiting our understanding of the shape of the learning curve and its underlying…  Continue reading →

Theta sequences and phase precession shape hippocampal activity and are considered key underpinnings of memory formation. Theta sequences are sweeps of spikes from multiple cells, tracing trajectories from past to future. Phase precession is the correlation between theta firing phase…  Continue reading →