When a sound predicts the potential arrival of a reinforcer, the subject learns the time at which that reinforcer may arrive or is available. The amygdala, and in particular its basolateral (BLA) part is critical for the emotional/motivational aspect of learning. On the other hand, the medial prefrontal cortex (mPFC) and the dorsomedial striatum (DMS) form a network involved in interval timing and behavior. Because of its direct efferences to both the mPFC) and the DMS, BLA is in an ideal position to influence the mPFC-DMS network. I will present a series of experiments in rats to highlight the role of BLA in modulating/controlling the expectancy of a reinforcer, in particular in its temporal aspect.
Salle de Conférence Lavoisier A – Campus Saint-Germain-des-Prés – 45 rue des Saints-Pères, 75006 Paris – 22 Septembre 2023 à 11:30