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    événements, séminaires

    9 Décembre 2022 – Jean-Michel Perrin (Institut de Biologie Paris-Seine) – Reconstructing rodent and human neuronal networks to model neurodegenerative syndromes

    Human brain is a complex organ composed of several hundred billions of cells and even more numerous interconnected cellular interactions. There is a high demand for experimental models to study these interactions in various contexts, ranging from cognitive sciences to studies…  Continue reading

    événements, séminaires

    28 Octobre 2022 – Christophe Bernard (Institut de Neurosciences des Systèmes, Université d’Aix-Marseille) – The timescale dynamics of epilepsies: from seconds to decades

    Continuous long-term recordings (months to years) in patients with epilepsy directly show that seizures are regulated not only in a circadian manner, but also on a much slower time scale (days to weeks). They strongly suggest the existence of specific…  Continue reading

    événements, séminaires

    14 Octobre 2022 – Anne-Noël Samaha (Université de Montréal) – Addiction to cocaine: How you take the drug is more decisive than how much

    Exceptionnellement ce séminaire aura lieu en Salle des thèses (3ème étage) – Campus Saint-Germain-des-Prés, 45 rue des Saints-Pères, 75006 Paris A widely used preclinical procedure to study features of cocaine addiction involves allowing laboratory animals to take drug continuously,…  Continue reading

    événements, séminaires

    7 Octobre 2022 – Fekrije Selimi  (Collège de France, Paris)- The developmental history of the molecular synaptic code controlling excitatory connectivity

    The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with a limited number of partners and on precise subcellular localizations. Understanding what controls this specificity is…  Continue reading

    événements, séminaires

    23 Septembre 2022 – Sébastian Bouret (ICM, Paris) – Neural basis of decision-making in primates. In the lab and beyond

    The presentation will cover the cognitive and neurobiological functions underlying cost-benefits decision making in primates. After covering data from laboratory experiments, I will present recent studies aimed at understanding how these data can help understand how specific neuro-cognitive operations allow…  Continue reading

    événements, séminaires

    24 Juin 2022 – Pierre Paoletti (Institut de Biologie de l’ENS, Paris) – New lights on neurotransmission: from molecular optogenetics to excitatory glycine receptors

    The function of the human brain and its remarkable capacity for information storage and experience-dependent change hinge on the dynamics of chemical synapses – main ‘contact points’ between neurons. My team has a long-standing interest in studying the molecular principles…  Continue reading

    événements, séminaires

    Jeudi, 12 Mai 2022 – Melissa Bowerman (Keele University, UK) – Combining bioinformatic and drug repurposing approaches to develop second-generation therapies for spinal muscular atrophy

    Spinal muscular atrophy (SMA) is a devastating childhood disease caused by loss of function of the survival motor neuron (SMN) gene, leading to the death of nerve and muscle cells. The first SMN gene replacement therapies have recently been approved…  Continue reading