events, seminars
8 Octobre 2021 – Laurent Venance (Collège de France, Paris) – Striatal synaptic plasticity and procedural learning
Our main interest is how neural networks of the brain support its cognitive capacities. We are focusing on the procedural learning, i.e. the acquisition of skills through repeated performance and practice of a behavior in response to external cues. Cortex/thamus-basal… Continue reading
events, seminars
October 8th, 2021 – Laurent Venance (Collège de France, Paris) – Striatal synaptic plasticity and procedural learning
Our main interest is how neural networks of the brain support its cognitive capacities. We are focusing on the procedural learning, i.e. the acquisition of skills through repeated performance and practice of a behavior in response to external cues. Cortex/thamus-basal… Continue reading
events, seminars
October 1st, 2021 – Alberto Bacci (ICM, Paris) – Connectivity and plasticity of neocortical basket cells
In the neocortex, perisomatic inhibition onto principal pyramidal neurons (PNs) determines the dynamic range of pyramidal neuron responses during sensory processing and drive several forms of network oscillations, believed to be the network correlate of several cognitive functions. The inhibitory… Continue reading
events, seminars
September 24th, 2021 – Séverine Boillée (ICM, Paris) – Modifying macrophages at the periphery has the capacity to modify microglial reactivity and to extend ALS mouse survival
Microglia, the macrophage of the CNS and peripheral macrophages, combined, have been implicated in Amyotrophic Lateral Sclerosis (ALS), the most common adult-onset motor neuron disease, but without discriminating their respective roles. Since we have shown that microglial cells participated to… Continue reading
events, seminars
November 6, 2020 – Stéphane Dieudonné (ENS, Paris) – A sequential strategy for multi photon actuation and recording of membrane voltage in awake animals
Technologies for recording and manipulating neuronal membrane potential in vivo in defined neuronal populations with high fidelity will be essential to understand how information is represented, processed, and propagated in the brain. Genetically encoded voltage indicators and optogenetic actuators are… Continue reading
events, seminars
October 16, 2020 – Philippe Faure (IBPS, Paris) – Exploratory behavior, individual trait and nicotine addiction: the role of dopamine
Consistent individual differences in behaviours represent an ubiquitous feature in animal populations. These behavioural differences among individuals define personality and have been linked to the susceptibility to addiction. Indeed, the susceptibility to develop drug addiction differs substantially between individuals and some traits that characterize an individual,… Continue reading
events, seminars, videos
October 9, 2020 – Gregory Gauvain (Institut de la Vision, Paris) – Optogenetics for vision restoration: toward clinical trials
Using vector and genetic constructs most suitable for vision restoration in patients with retinopathies, we have demonstrated temporal resolution compatible with highly dynamic visual scenes and a visual acuity above legal blindness.
Captation et conception vidéo: Service audiovisuel de Paris Descartes.
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events, seminars, videos
October 2, 2020 – Bassem Hassan (ICM, Paris) – The neuroscience of why flies are people
The genome versus experience dichotomy has dominated understanding of behavioral individuality. By contrast, the role of nonheritable noise during brain development in behavioral variation is understudied. Using Drosophila melanogaster, we demonstrate a link between stochastic variation in brain wiring and… Continue reading
events, seminars
Seminar program 2020
Friday at 11:30 a.m. in Conference room R229
17/01 Martin Giurfa (Research Center, University of Toulouse, France)24/01 Naguib Mechawar (Human brain bank, McGill University, Montréal, Canada)07/02 Ruben Portugues (Max Planck Institute of Neurobiology, Martinsried, Germany)25/09 Caroline Rouaux… Continue reading
events, seminars, videos
September 25, 2020 – Caroline Rouaux (Inserm U1118, University of Strasbourg, France) – Evaluation of the corticofugal hypothesis in ALS
Amyotrophic lateral sclerosis (ALS) is the third most frequent neurodegenerative disease after Alzheimer’s and Parkinson’s diseases, and the most frequent disease of the adult motoneuron. Clinically and histopathologically, ALS is defined as the simultaneous degeneration of corticospinal neurons (CSN) in… Continue reading