Where:

Amphithéâtre Vulpian, locomotion

Université Paris Descartes,

12 rue de l’École de Médecine,

75006 Paris

Organizers:

Jacqueline Fagard (Laboratoire psychologie de la Perception, UMR 8242 CNRS -Paris Descartes), Valérie Mezger (Epigénétique et Destin Cellulaire, UMR7216 CNRS – Paris Diderot), Claire Legay and Claude Meunier (Centre de Neurophysique, Physiologie et Pathologie, UMR8119 CNRS – Paris Descartes)

Program:

9:00-9:30 :   Breakfast and Welcome Address

9:30-10:30 : Keynote Lecture : “EPIGENETICS IN DEVELOPMENT AND DISEASE : LESSONS FROM THE X CHROMOSOME” by Edith Heard, Collège de France, Paris

10h30 – 10h40: short presentation of Diagénode system , by Jérome Kroonen

10:40-12:40 : From Biochemical mechanisms to Pathology

• Jonathan Weitzman (Epigénétique et destin cellulaire, Paris Diderot)
  • Challenges of translational epigenetics for the neurosciences
• Bérénice Benayoun (University of Califormia – Davies school of Gerontology,L.A, USA),
  • Epigenome and transcriptome changes across tissues during mouse aging

• Johannes Gräff (Brain Mind Institute, École Polytechnique Fédérale Lausanne (EPFL),Switzerland)
  • Epigenetic Mechanisms in Alzheimer’s Disease

12:30-14:00 Lunch in Galerie Saint-Germain

14:00-16:00 Epigenetics and Brain development

• Giacomo Cavalli (Institut de Génétique humaine, Montpellier)
  • The 3D genome fingerprint of neuronal differentiation

• Claudine Junien (UVSQ, INRA, Paris, France)

A glance through epigenetic brain sex differences

• Tracy Bale (Perelman School of Medecine, University of Pennsylvania, USA)             
  • Maternal stress and epigenetic programming of the developing brain

16:00-16:30 Coffee break

16:30-18h30: An epigenetic determinism?

• Marc Potenza (University of Yale, USA)
  • Epigenetic considerations for behavioral addictions: Gene and environmental contributions to gambling disorder
• Ernesto Burgio (ECERI, Brussels, Belgium and ISDE, Arezzo, Italy)
  • Brain Evolution and Neurodevelopmental Disorders : From Genetics to Epigenetics

• Francesca Merlin (IHPST – CNRS & Université Paris 1 Panthéon-Sorbonne)
  • Conceptual and epistemological issues in brain epigenetics and beyond 

18:30-19:00 Conclusion and Refreshments

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