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    events, seminars, videos

    Friday, May 19th : Na Ji (Janelia Research Campus, Virginia, USA)

    thumbnail of 2017 JiiNeuroscience Seminar Series:
    Friday, May 19th, 2017 , 11:30 am, Salle des Conférences (R229), Centre Universitaire des Saints-Pères, 45 rue des Saints-Pères, 75006 Paris

    Na Ji, PhD, Janelia Research Campus, Virginia, USA

    Title: Probing neural circuits with shaped light

    Captation et conception vidéo: Service audiovisuel de Paris Descartes.

    video25-75927Video sur MédiasD

    Summary:
    To understand computation in the brain, one needs to understand the input-output relationships for neural circuits and the anatomical and functional relationships between individual neurons therein. Optical microscopy has emerged as an ideal tool in this quest, as it is capable of recording the activity of neurons distributed over millimeter dimensions with sub-micron spatial resolution. I will describe how we use concepts in astronomy and optics to develop next-generation microscopy methods for imaging neural circuits at higher resolution, greater depth, and faster speed. By shaping the wavefront of the light, we have achieved synapse-level spatial resolution through the entire depth of primary visual cortex, optimized microendoscopes for imaging deeply buried nuclei, and developed a video-rate (30 Hz) volumetric imaging method. We apply these methods to understanding neural circuits, using the mouse primary visual cortex as our model system.

    Those interested in meeting with the speaker please contact Valentina Emiliani.